if you're talking like a Hypertech PoS, i don't know. i've had mine tuned by shipping the PCM out, i've had one sent to me with a core charge so i could keep driving & send my old one back, and i've also datalogged with a laptop & emailed the files to/from the tuner then downloaded to truck from laptop.
i've also heard of the AutoCal that's a handheld programmer your tuner can load your file onto & then you can swap between stock & a few stored tunes whenever you need.
there's a few ways to skin the cat depending on who tuned your truck & the methods they offer.