Thank You Dave and John for the info,

Yes I believe I have the 4L80e tranny.

I think my biggest concerns are:

Will the small block fit in the same engine mount location as the big block sits?
Will I be able to keep the stock gauge cluster and all interior items stock? I am guessing this is where the wiring re-work or aftermarket harness comes in. (re-work or harness in engine compartment hooks up to firewall plug to keep interior stock).
Will I use the radiator from the big block or have to get the 6.0L rad?
Exhaust... I know it will not bolt up from the big block but how far to I have to modify, from motor to cat...the whole exhaust?

I know there are more questions I just need to sit and think about this. Thanks for you help this far!
Willis