6.0, 5.3, 5.7 have diff combustion chamber sizes. If u put 6.0 heads on a 5.3 u will loose compression
Not if they're all the same casting number. 799/243's are the same no matter what engine they come off of. 5.3, 5.7, 6.0 have all used 243/799 heads at some point, and they're all the same.