the stock TB is 87mm on the truck intake, but will be able to use a 90mm TB. also its a dbw, he didnt mention what wiring harness he'll be going with unless i missed it.
my friend used that 220/224 113+4 cam with a TB stall(2000-2400 foot brake) an still pulled his travel trailor. i dunno what the mpg was but it never struggled, he's got 4:10s. dont be scared run that 218/220 cam
oh also id use a set of Patriot Dual Gold(.600 might be wrong) or Extreme(.660) valve springs
throw a set of LTs an a magnaflow muffler on it.
good luck with the build man...im looking for low/mid 14s in my ECSB LSx swap.
2008 GMC CCSB 6.2/6L80e swap
Gen IV 5.3/60e swap 1994 ecsb W/T